Ambrisentan Tablets and Ravicti Oral Liquid

• Generic Name: ambrisentan
• Dosage Forms: tablet, film coated
• Other Brand Names: Letairis

Ambrisentan lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

Ambrisentan is used to treat pulmonary arterial hypertension (PAH) in adults. It improves your ability to exercise and prevents your condition from getting worse. Ambrisentan is sometimes used with a medicine called tadalafil (Adcirca).

For women, ambrisentan is available only from a certified pharmacy under a special program. You must be registered in the program and sign agreements to use birth control and undergo pregnancy and blood testing.

Ambrisentan may also be used for purposes not listed in this medication guide.

• Generic Name: glycerol phenylbutyrate
• Dosage Forms: oral liquid
• Other Brand Names: Ravicti

Ravicti (glycerol phenylbutyrate) binds with other substances in the liver and kidneys to help eliminate nitrogen from the body. Excess nitrogen can cause hyperammonemia, a build-up of ammonia in the blood. Ammonia is very toxic when it circulates in blood and tissues and can cause permanent brain damage, coma, or death.

Ravicti helps prevent a build-up of ammonia in the blood in people with urea cycle disorder. This medicine is used in adults, children and infants. Ravicti will not treat hyperammonemia.

Ravicti is usually given together with a low-protein diet and sometimes dietary supplements.