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Amidate and Verelan

Determining the interaction of Amidate and Verelan and the possibility of their joint administration.

Check result:

Amidate <> Verelan

Relevance: 23.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using etomidate together with verapamil may increase the effects of etomidate. You should be closely monitored for prolong breathing cessation. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Verapamil may enhance the anesthetic effect of etomidate. Prolonged anesthesia and profound respiratory depression could result. The mechanism is unknown.

MANAGEMENT: The clinician should be aware of the risk of respiratory arrest and the need for close monitoring and ventilatory support.

References

Moore C "Potentiation of etomidate anesthesia by verapamil: a report of two cases." Hosp Pharm 24 (1989): 24

Amidate

Generic Name: etomidate

Brand name: Amidate

Synonyms: n.a.

What is Amidate?

Verelan

Generic Name: verapamil

Brand name: Calan, Calan SR, Isoptin SR, Verelan, Isoptin, Isoptin IV, Covera-HS, Verelan PM

Synonyms: Verelan (Oral)

What is Verelan?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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