Amifampridine Tablets (Ruzurgi) and Delavirdine Mesylate

• Generic Name: amifampridine
• Dosage Forms: n.a.
• Other Brand Names: Firdapse, Ruzurgi

• It is used to treat myasthenic syndrome of Eaton-Lambert.

• Generic Name: delavirdine
• Dosage Forms: n.a.
• Other Brand Names: Rescriptor

Treatment of HIV-1 infection in adults; usually used in conjunction with 2 HIV nucleoside reverse transcriptase inhibitors (NRTIs).

Experts state delavirdine not recommended for initial treatment regimens in antiretroviral-naive adults because of inferior virologic efficacy and inconvenient dosing regimen.

Data insufficient comparing delavirdine regimens to the preferred 3-drug regimens for initial treatment in antiretroviral-naive adults; consider that the proportion of clinical study patients responding to regimen of delavirdine and 2 NRTIs with sustained plasma HIV-1 levels <400 copies/mL over 1 year has been relatively low.