Aminocaproic and Canakinumab Subcutaneous

• Generic Name: aminocaproic acid
• Dosage Forms: tablet
• Other Brand Names: Amicar

Aminocaproic acid is a man-made form of a protein that occurs naturally in the body and helps the blood to clot.

Aminocaproic acid is used to treat bleeding episodes in people with certain medical conditions such as aplastic anemia (lack of blood cells and platelets), cirrhosis of the liver, placenta abruptio (early separation of the placenta in pregnancy), urinary bleeding, and certain types of cancer.

Aminocaproic acid is also used to prevent bleeding after heart surgery or placement of a shunt near the liver to control high blood pressure.

Aminocaproic acid may also be used for purposes not listed in this medication guide.

• Generic Name: canakinumab
• Dosage Forms: n.a.
• Other Brand Names: Ilaris

Canakinumab injection is used to treat cryopyrin-associated periodic syndromes (CAPS). This also includes familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS). CAPS is a rare, inherited disease of the immune system. It occurs when the body produces too much of a chemical called interleukin-1 beta. This chemical causes inflammation, and patients with CAPS may have a fever, headache, skin rash, joint or muscle pain, or unusual tiredness or weakness.

Canakinumab helps prevent inflammation by keeping the interleukin-1 beta from working properly. Canakinumab also treats adults and children with other autoinflammatory periodic fever syndromes, such as tumor necrosis factor receptor associated periodic syndrome (TRAPS), hyperimmunoglobulin D syndrome (HIDS)/mevalonate kinase deficiency (MKD), and familial Mediterranean fever (FMF).

Canakinumab is also used to treat active systemic juvenile idiopathic arthritis (SJIA) in children 2 years of age and older.

Canakinumab is to be given only by or under the direct supervision of a doctor.