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Aminophylline injection and Daliresp

Determining the interaction of Aminophylline injection and Daliresp and the possibility of their joint administration.

Check result:

Aminophylline injection <> Daliresp

Relevance: 25.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with theophylline may increase the systemic exposure to roflumilast and its pharmacologically active N-oxide metabolite. In a drug interaction study, the total exposure to roflumilast and roflumilast N-oxide increased by 8% with concomitant theophylline. The clinical significance is unknown.

References

"Product Information. Daxas (roflumilast)." Nycomed Inc, Princeton, NJ.
"Product Information. Daliresp (roflumilast)." Astra-Zeneca Pharmaceuticals, Wilmington, DE.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Aminophylline injection

Generic Name: aminophylline

Brand name: Phyllocontin, Truphylline

Synonyms: Aminophylline (injection), Aminophylline

What is Aminophylline injection?

Daliresp

Generic Name: roflumilast

Brand name: Daliresp

Synonyms: n.a.

What is Daliresp?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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