Aminophylline injection and Ketalar

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using ketamine together with aminophylline may cause seizures. Contact your doctor if you experience confusion, seizures, and other mental status changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Cases of extensor-type seizures have been reported in four asthmatic patients who received aminophylline following induction of anesthesia with ketamine. Causality was not clearly determined due to the presence of other anesthetics. Animal studies suggest that the mechanism of this interaction may involve a lowering of the seizure threshold. Theophylline, dyphylline, and oxtriphylline may also interact.

MANAGEMENT: If aminophylline and ketamine must be used concomitantly, caution should be exercised.

Aminophylline injection

Generic Name: aminophylline

Brand name: Phyllocontin, Truphylline

Synonyms: Aminophylline (injection), Aminophylline

What is Aminophylline injection?

Ketalar

Generic Name: ketamine

Brand name: Ketalar

Synonyms: n.a.

What is Ketalar?