Aminophylline injection and Mycophenolate Mofetil Tablets
Determining the interaction of Aminophylline injection and Mycophenolate Mofetil Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:In vitro studies have shown that mycophenolic acid in concentrations up to 100 mcg/mL decreases protein binding of theophylline from 53% to 45%. The clinical significance of this interaction is unknown. Decreased protein binding theoretically could lead to increased plasma theophylline concentrations. However, clinical toxicity has not been reported. It may be appropriate to monitor more closely patients receiving theophylline or other methylxanthine derivatives with mycophenolic acid products. Patients should be advised to contact their physician if they experience potential symptoms of theophylline toxicity such as nausea, vomiting, diarrhea, headache, restlessness, insomnia, and irregular heartbeat.
- "Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Generic Name: aminophylline
Brand name: Phyllocontin, Truphylline
Synonyms: Aminophylline (injection), Aminophylline
Generic Name: mycophenolate mofetil
Brand name: Cellcept, Myfortic, MMF
Synonyms: Mycophenolate mofetil (oral/injection), Mycophenolate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aminophylline injection-Mycophenolate sodium
- Aminophylline injection-Mycophenolate Suspension
- Aminophylline injection-Mycophenolate Tablets
- Aminophylline injection-Mycophenolate Tablets Delayed Release
- Aminophylline injection-Mycophenolic acid
- Aminophylline injection-Mycophenolic Acid Delayed-Release Tablets
- Mycophenolate Mofetil Tablets-Aminophylline Intravenous
- Mycophenolate Mofetil Tablets-Aminophylline Oral Solution
- Mycophenolate Mofetil Tablets-Aminophylline Tablets
- Mycophenolate Mofetil Tablets-AminoProtect
- Mycophenolate Mofetil Tablets-Aminosalicylate sodium
- Mycophenolate Mofetil Tablets-Aminosalicylic Acid