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Aminophylline Intravenous and Anesthesia S/I-40

Determining the interaction of Aminophylline Intravenous and Anesthesia S/I-40 and the possibility of their joint administration.

Check result:

Aminophylline Intravenous <> Anesthesia S/I-40

Relevance: 24.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Theophyllines may antagonize the sedative effects of propofol. In one patient receiving ventilatory support, the amount of propofol required for sedation decreased following discontinuation of an aminophylline infusion. Further study is needed to confirm this interaction.

References

Taylor BL, Collins C "Aminophylline and propofol: apparent antagonism." Anaesthesia 43 (1988): 508

Aminophylline Intravenous

Generic Name: aminophylline

Brand name: Phyllocontin, Truphylline

Synonyms: Aminophylline (Intravenous)

What is Aminophylline Intravenous?

Anesthesia S/I-40

Generic Name: propofol

Brand name: Diprivan, Propoven

Synonyms: Propofol

What is Anesthesia S/I-40?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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