Aminophylline Oral Solution and Zovirax (Acyclovir Capsules and Tablets)
Determining the interaction of Aminophylline Oral Solution and Zovirax (Acyclovir Capsules and Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that the combination of a methyl xanthine with acyclovir may lead to elevated theophylline levels potentiating pharmacologic and adverse effects. The mechanism may be due to inhibition of theophylline oxidative metabolism. Clinical and laboratory monitoring is warranted if these agents are given concurrently. Patients receiving this combination should be advised to report any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, or irregular heartbeat to their physician.
- Maeda Y, Konishi T, Omoda K, Takeda Y, Fukuhara S, Fukuzawa M, Ohune T, Tsuya T, Tsukiai S "Inhibition of theophylline metabolism by aciclovir." Biol Pharm Bull 19 (1996): 1591-5
Generic Name: aminophylline
Brand name: Phyllocontin, Truphylline
Synonyms: Aminophylline (injection), Aminophylline
Generic Name: acyclovir
Brand name: Sitavig, Zovirax
Synonyms: Zovirax
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aminophylline Oral Solution-Zovirax (Acyclovir Cream)
- Aminophylline Oral Solution-Zovirax (Acyclovir Injection)
- Aminophylline Oral Solution-Zovirax (Acyclovir Ointment)
- Aminophylline Oral Solution-Zovirax (Acyclovir Suspension)
- Aminophylline Oral Solution-Zovirax Cream
- Aminophylline Oral Solution-Zovirax Injection
- Zovirax (Acyclovir Capsules and Tablets)-Aminophylline Tablets
- Zovirax (Acyclovir Capsules and Tablets)-AminoProtect
- Zovirax (Acyclovir Capsules and Tablets)-Aminosalicylate sodium
- Zovirax (Acyclovir Capsules and Tablets)-Aminosalicylic Acid
- Zovirax (Acyclovir Capsules and Tablets)-Aminosyn
- Zovirax (Acyclovir Capsules and Tablets)-Aminosyn 10%