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Aminosalicylate sodium and Isoniazid Syrup

Determining the interaction of Aminosalicylate sodium and Isoniazid Syrup and the possibility of their joint administration.

Check result:

Aminosalicylate sodium <> Isoniazid Syrup

Relevance: 23.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Aminosalicylic acid in an immediate release preparation has been reported to produce a reduction in the acetylation of isoniazid (INH), especially in fast acetylators. Studies have not been conducted with the delayed-release formulation of aminosalicylic acid. Due to lower serum levels with the delayed-release formulation of aminosalicylic acid, it is expected that a reduced effect on acetylation of INH will occur. Toxicity has not been reported.

References

"Product Information. Paser Granules (aminosalicylic acid)." Jacobus Pharmaceutical Company, Princeton, NJ.

Aminosalicylate sodium

Generic Name: aminosalicylic acid

Brand name: Paser

Synonyms: Aminosalicylate sodium (Oral)

What is Aminosalicylate sodium?

Isoniazid Syrup

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: Isoniazid

What is Isoniazid Syrup?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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