Amitriptyline Hydrochloride and Peginterferon beta-1a Subcutaneous

• Generic Name: amitriptyline
• Dosage Forms: n.a.
• Other Brand Names: Vanatrip, Elavil, Endep

Management of major depressive disorder.

Has been used in fixed combination with chlordiazepoxide in the management of depression associated with moderate to severe anxiety.

Management of moderate to severe anxiety and/or agitation (in fixed combination with perphenazine) in patients with depressed mood.

Management of severe anxiety and/or agitation (in fixed combination with perphenazine) in patients with depression.

Management of depression and anxiety (in fixed combination with perphenazine) in association with chronic physical disease.

Management of acute depressive episodes (in fixed combination with perphenazine) in patients with schizophrenia.

Second-line agent in attention deficit hyperactivity disorder (ADHD) patients unable to tolerate or unresponsive to stimulants; should be used only under close supervision.

Associated with a narrower margin of safety than some other therapeutic agents; use only if clearly indicated and with careful monitoring, including baseline and subsequent determinations of ECG and other parameters.

Medium to high efficacy for prophylaxis of migraine headache.

Equivocal efficacy for management of eating disorders (e.g., bulimia, anorexia nervosa); avoid use in underweight individuals and in those exhibiting suicidal ideation.

Has been used for the short-term management of acute depressive episodes in bipolar disorder.

TCAs associated with a greater risk of precipitating hypomania or manic episodes than other classes of antidepressants; should always be used in combination with a mood stabilizer (e.g., lithium).

Among the drugs of choice for the symptomatic treatment of postherpetic neuralgia.

Less effective for insomnia and associated with more serious adverse reactions than conventional hypnotics.

• Generic Name: peginterferon beta-1a
• Dosage Forms: n.a.
• Other Brand Names: Plegridy, Plegridy Pen, Plegridy Pen Starter Pack, Plegridy Starter Pack

Peginterferon beta-1a injection is used to treat the relapsing forms of multiple sclerosis (MS). Peginterferon beta-1a will not cure MS, but it may slow some of the disabling effects and decrease the number of relapses of the disease. Peginterferons are natural substances that are produced in the body to help fight infections. Peginterferon beta-1a is a synthetic (man-made) version of these substances.

Peginterferon beta-1a is available only with your doctor's prescription.