Amjevita Subcutaneous and Pilocarpine Hydrochloride

• Generic Name: adalimumab
• Dosage Forms: n.a.
• Other Brand Names: Humira, Humira Pen, Humira Pen Crohns/UlcerColit/HidraSuppur, Humira Pen Psoriasis/Uveitis Starter Package, Humira Pediatric, Humira Pediatric Crohn's Disease Starter Pack, Humira Pre-Filled Syringe, Humira Pen Psoriasis/Uveitis/Adol HidraSuppur Starter Pack, Humira Pen Crohns/Ulcer Colitis/Hidradenitis Suppurati StrPk

Adalimumab-atto injection is used to treat the symptoms and prevent the progression of moderate to severely active rheumatoid arthritis and ankylosing spondylitis. It is used in children 4 years of age and older for juvenile idiopathic arthritis. This medicine is also used to treat psoriatic arthritis, which is a type of arthritis that causes pain and swelling in the joints along with patches of scaly skin on some areas of the body. Psoriatic arthritis usually occurs with a skin condition called psoriasis. Adalimumab-atto may be used alone or in combination with medicines (eg, methotrexate).

Adalimumab-atto injection is also used to treat the symptoms of active Crohn’s disease in patients who have not been helped by other medicines (eg, infliximab). It is also used to treat moderate to severe ulcerative colitis in patients who have been treated with other medicines (eg, azathioprine, corticosteroids, or 6-mercaptopurine) that did not work well. This medicine may also be used to treat moderate to severe chronic plaque psoriasis, which is a skin disease with red patches and white scales that don’t go away.

This medicine is available only with your doctor’s prescription.

• Generic Name: pilocarpine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Pilocar, Pilopine-HS, Pilostat, Isopto Carpine, Adsorbocarpine, Pilagan with C Cap, Ocu-Carpine, Ocusert, Piloptic-1/2, Piloptic-1, Akarpine, Piloptic-2, Piloptic-3, Piloptic-4, Piloptic-6

Symptomatic treatment of radiation-induced dry mouth (xerostomia) in patients with head and neck cancer.

Symptomatic treatment of dry mouth in patients with Sjögren syndrome.

There are few comparative studies of pilocarpine and cevimeline (a similar muscarinic agonist). Although both drugs can increase salivary flow and improve symptoms of dry mouth, adverse effects may differ based on differences in selectivity and affinity for muscarinic receptors. (See Actions.)