Amlodipine and benazepril and Nicardipine Capsules
Determining the interaction of Amlodipine and benazepril and Nicardipine Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Calcium channel blockers and angiotensin converting enzyme (ACE) inhibitors may have additive hypotensive effects. While these drugs are often safely used together, careful monitoring of the systemic blood pressure is recommended during coadministration, especially during the first one to three weeks of therapy.
- Di Somma S, et al "Antihypertensive effects of verapamil, captopril and their combination at rest and during dynamic exercise." Arzneimittelforschung 42 (1992): 103
- Kaplan NM "Amlodipine in the treatment of hypertension." Postgrad Med J 67 Suppl 5 (1991): s15-9
- DeQuattro V "Comparison of benazepril and other antihypertensive agents alone and in combination with the diuretic hydrochlorothiazide." Clin Cardiol 14 (1991): iv28-32;
- Sun JX, Cipriano A, Chan K, John VA "Pharmacokinetic interaction study between benazepril and amlodipine in healthy subjects." Eur J Clin Pharmacol 47 (1994): 285-9
Generic Name: amlodipine / benazepril
Brand name: Lotrel
Synonyms: Amlodipine and Benazepril
Generic Name: nicardipine
Brand name: Cardene IV, Cardene SR, Cardene
Synonyms: NiCARdipine, Nicardipine (oral/injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Amlodipine and benazepril-NiCARdipine Hydrochloride
- Amlodipine and benazepril-Nicardipine Injection
- Amlodipine and benazepril-Nicardipine Intravenous
- Amlodipine and benazepril-Nicardipine oral/injection
- Amlodipine and benazepril-NicAzel Doxy Kit
- Amlodipine and benazepril-NicAzel Forte
- Nicardipine Capsules-Amlodipine and celecoxib
- Nicardipine Capsules-Amlodipine and olmesartan
- Nicardipine Capsules-Amlodipine and Olmesartan Medoxomil
- Nicardipine Capsules-Amlodipine and perindopril
- Nicardipine Capsules-Amlodipine and telmisartan
- Nicardipine Capsules-Amlodipine and valsartan