Amlodipine and perindopril and Gentamicin
Determining the interaction of Amlodipine and perindopril and Gentamicin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data from animal studies suggest that perindopril may increase the risk of gentamicin-induced nephrotoxicity. The mechanism may be related to inhibition of the renin-angiotensin system. Until more information is available, caution should be used when these drugs are given together and renal function should be closely monitored.
- "Product Information. Aceon (perindopril)." Solvay Pharmaceuticals Inc, Marietta, GA.
Generic Name: amlodipine / perindopril
Brand name: Prestalia
Synonyms: Perindopril and Amlodipine
Generic Name: gentamicin
Brand name: Garamycin, Cidomycin, Septopal
Synonyms: Gentamicin (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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