Amlodipine and telmisartan and Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials
Determining the interaction of Amlodipine and telmisartan and Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using telmisartan together with dalteparin may increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney failure, muscle paralysis, irregular heart rhythm, and cardiac arrest. You may be more likely to develop hyperkalemia while using these medications if you are elderly, dehydrated, or have kidney disease, diabetes, or advanced heart failure. Regular or long-term use of nonsteroidal anti-inflammatory drugs such as ibuprofen or naproxen (Aleve) may also increase your risk. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, as these may be symptoms of hyperkalemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) and heparin or low molecular weight heparins may increase the risk of hyperkalemia. ACE inhibitors, ARBs, and some heparins individually have been associated with increased potassium levels or hyperkalemia. Patients with renal impairment, diabetes, old age, and severe or worsening heart failure may be at a greater risk.
MANAGEMENT: Caution is advised if ACE inhibitors or ARBs are used with heparin or low molecular weight heparin. Serum potassium and renal function should be checked regularly.
- "Product Information. Micardis (telmisartan)." Boehringer-Ingelheim, Ridgefield, CT.
- "Product Information. Diovan (valsartan)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Avapro (irbesartan)." Bristol-Myers Squibb, Princeton, NJ.
- "Product Information. Atacand (candesartan)." Astra Pharmaceuticals, Wayne, PA.
- "Product Information. Benicar (olmesartan)." Sankyo Parke Davis, Parsippany, NJ.
- "Product Information. Teveten (eprosartan)." SmithKline Beecham, Philadelphia, PA.
- Perazella MA "Drug-induced hyperkalemia: old culprits and new offenders." Am J Med 109 (2000): 307-14
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Cozaar (losartan)." Merck & Co, Inc, West Point, PA.
- "Product Information. Edarbi (azilsartan)." Takeda Pharmaceuticals America, Lincolnshire, IL.
Generic Name: amlodipine / telmisartan
Brand name: Twynsta
Synonyms: Telmisartan and Amlodipine
Generic Name: dalteparin
Brand name: Fragmin
Synonyms: Dalteparin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Amlodipine and telmisartan-Dalteparin Multi-Dose Vials
- Amlodipine and telmisartan-Dalteparin Sodium
- Amlodipine and telmisartan-Dalteparin Subcutaneous
- Amlodipine and telmisartan-Dalvance
- Amlodipine and telmisartan-Danaparoid
- Amlodipine and telmisartan-Danaparoid Subcutaneous
- Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials-Amlodipine and valsartan
- Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials-Amlodipine Besylate
- Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials-Amlodipine Suspension
- Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials-Amlodipine Tablets
- Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials-Amlodipine, hydrochlorothiazide, and olmesartan
- Dalteparin Ampules, Prefilled Syringes, and Single-Dose Vials-Amlodipine, hydrochlorothiazide, and valsartan