Amlodipine and telmisartan and Mycophenolate Mofetil Injection Solution
Determining the interaction of Amlodipine and telmisartan and Mycophenolate Mofetil Injection Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Telmisartan may decrease the blood levels and effects of mycophenolate mofetil. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with telmisartan may decrease the plasma concentrations and therapeutic effects of mycophenolate mofetil (MMF). Concomitant use of telmisartan with MMF resulted in an approximately 30% decrease in mycophenolic acid (MPA) concentrations. The proposed mechanism is increased clearance due to telmisartan-mediated induction of UGT1A9. Adverse effects, such as graft rejection in transplant patients, have not been reported.
MANAGEMENT: Until more information is available, caution is advised when telmisartan is used concomitantly with mycophenolate mofetil. Dosage adjustments as well as clinical and laboratory monitoring should be considered.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Generic Name: amlodipine / telmisartan
Brand name: Twynsta
Synonyms: Telmisartan and Amlodipine
Generic Name: mycophenolate mofetil
Brand name: Cellcept, Myfortic, MMF
Synonyms: Mycophenolate mofetil (oral/injection), Mycophenolate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Amlodipine and telmisartan-Mycophenolate Mofetil Oral Suspension
- Amlodipine and telmisartan-Mycophenolate mofetil oral/injection
- Amlodipine and telmisartan-Mycophenolate Mofetil Tablets
- Amlodipine and telmisartan-Mycophenolate sodium
- Amlodipine and telmisartan-Mycophenolate Suspension
- Amlodipine and telmisartan-Mycophenolate Tablets
- Mycophenolate Mofetil Injection Solution-Amlodipine and valsartan
- Mycophenolate Mofetil Injection Solution-Amlodipine Besylate
- Mycophenolate Mofetil Injection Solution-Amlodipine Suspension
- Mycophenolate Mofetil Injection Solution-Amlodipine Tablets
- Mycophenolate Mofetil Injection Solution-Amlodipine, hydrochlorothiazide, and olmesartan
- Mycophenolate Mofetil Injection Solution-Amlodipine, hydrochlorothiazide, and valsartan