Amlodipine, hydrochlorothiazide, and valsartan and Esbriet

• Generic Name: amlodipine / hydrochlorothiazide / valsartan
• Dosage Forms: n.a.
• Other Brand Names: Exforge HCT

Amlodipine is a calcium channel blocker. Hydrochlorothiazide is a thiazide diuretic (water pill). Valsartan is an angiotensin II receptor antagonist.

Amlodipine, hydrochlorothiazide, and valsartan is a combination medicine used to treat high blood pressure (hypertension).

Amlodipine, hydrochlorothiazide, and valsartan is usually given after other treatments have failed.

Amlodipine, hydrochlorothiazide, and valsartan may also be used for purposes not listed in this medication guide.

• Generic Name: pirfenidone
• Dosage Forms: capsule, tablet
• Other Brand Names: Esbriet

Esbriet (pirfenidone) is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). IPF causes scar tissue to form deep within your lungs. The scar tissue thickens and becomes stiff or thick over time, which can make it harder for your lungs to work. Decreased lung function can make it hard for you to breathe. Other medical problems can occur when your brain, heart, and other organs do not get enough oxygen.

The cause of IPF is often unknown, but this condition is a progressive disease that can be fatal.

Esbriet is not a cure for IPF, but this medicine may slow the progress of this disease.