Amlodipine, hydrochlorothiazide, and valsartan and Zavesca

• Generic Name: amlodipine / hydrochlorothiazide / valsartan
• Dosage Forms: n.a.
• Other Brand Names: Exforge HCT

Amlodipine is a calcium channel blocker. Hydrochlorothiazide is a thiazide diuretic (water pill). Valsartan is an angiotensin II receptor antagonist.

Amlodipine, hydrochlorothiazide, and valsartan is a combination medicine used to treat high blood pressure (hypertension).

Amlodipine, hydrochlorothiazide, and valsartan is usually given after other treatments have failed.

Amlodipine, hydrochlorothiazide, and valsartan may also be used for purposes not listed in this medication guide.

• Generic Name: miglustat
• Dosage Forms: capsule
• Other Brand Names: Zavesca

Zavesca (miglustat) reduces the formation of a certain protein in the body in people with type 1 Gaucher disease.

Gaucher disease is a genetic condition in which the body lacks the enzyme needed to break down certain fatty materials (lipids). Lipids can build up in the body, causing symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that are easily fractured.

Zavesca is used to treat mild to moderate type 1 Gaucher disease by people who cannot receive enzyme replacement therapy.

Zavesca may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, it is not a cure for this condition.

Zavesca may also be used for purposes not listed in this medication guide.