Amoxicillin, clarithromycin, and omeprazole and Retrovir (Zidovudine Injection)
Determining the interaction of Amoxicillin, clarithromycin, and omeprazole and Retrovir (Zidovudine Injection) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Clarithromycin may alter the rate at which zidovudine is absorbed. Conflicting reports indicate that peak serum zidovudine concentrations may increase or decrease. The proposed mechanism is a change in gastric emptying time induced by clarithromycin. It is recommended that these two agents be administered at least 2 hours apart.
- Gustavson LE, Chu SY, Mackenthun A, Gupta MS, Craft JC "Drug interaction between clarithromycin and oral zidovudine in HIV-1 infected patients." Clin Pharmacol Ther 53 (1993): 163
- Vance E, Watsonbitar M, Gustavson L, Kazanjian P "Pharmacokinetics of clarithromycin and zidovudine in patients with AIDS." Antimicrob Agents Chemother 39 (1995): 1355-60
Generic Name: amoxicillin / clarithromycin / omeprazole
Brand name: Omeclamox-Pak
Synonyms: Omeprazole, Clarithromycin, and Amoxicillin
Generic Name: zidovudine
Brand name: Retrovir
Synonyms: Retrovir (oral/injection), Retrovir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Amoxicillin, clarithromycin, and omeprazole-Retrovir (Zidovudine Syrup)
- Amoxicillin, clarithromycin, and omeprazole-Retrovir Infusion
- Amoxicillin, clarithromycin, and omeprazole-Retrovir Intravenous
- Amoxicillin, clarithromycin, and omeprazole-Retrovir oral/injection
- Amoxicillin, clarithromycin, and omeprazole-Revatio
- Amoxicillin, clarithromycin, and omeprazole-Revatio Injection
- Retrovir (Zidovudine Injection)-Amoxicillin/Clavulanate Chewable Tablets
- Retrovir (Zidovudine Injection)-Amoxicillin/Clavulanate Extended-Release Tablets
- Retrovir (Zidovudine Injection)-Amoxicillin/Clavulanate Suspension
- Retrovir (Zidovudine Injection)-Amoxicillin/Clavulanate Tablets
- Retrovir (Zidovudine Injection)-Amoxicot
- Retrovir (Zidovudine Injection)-Amoxil