Amphadase and Mepivacaine and Levonordefrin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

When hyaluronidase is added to a local anesthetic, the local anesthetic solution undergoes increased absorption, resulting in a shorter duration of action and possible increased frequency of systemic reactions. The clinical significance is unknown. It may be advisable to monitor the patient for altered anesthetic efficacy and side effects.

Amphadase

Generic Name: hyaluronidase

Brand name: Amphadase, Hylenex, Vitrase, Wydase, Hydase

Synonyms: n.a.

What is Amphadase?

Mepivacaine and Levonordefrin

Generic Name: levonordefrin / mepivacaine

Brand name: Carbocaine 2% with Neo-Cobefrin, Polocaine Dental, Scandonest 2% L

Synonyms: Carbocaine with Neo-Cobefrin

What is Mepivacaine and Levonordefrin?