Amphocin and Gengraf
Determining the interaction of Amphocin and Gengraf and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using amphotericin B together with cycloSPORINE. This can cause serious side effects on your kidneys. Call your doctor if your experience fever, chills, body aches, flu symptoms, and severe pain in your upper stomach spreading to your back. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The potential nephrotoxic effects of cyclosporine and amphotericin B may be additive.
MANAGEMENT: Alternate antifungal therapy is recommended. If these agents must be used concomitantly, renal function should be closely monitored.
- "Product Information. Abelcet (amphotericin B)." Liposome Company Inc, The, Princeton, NJ.
- Cockburn IT, Krupp P "An appraisal of drug interactions with sandimmun." Transplant Proc 21 (1989): 3845-50
- "Product Information. Sandimmune (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
- Kennedy M, Deeg J, Siegel M, et al "Acute renal toxicity with combined use of amphotericin B and cyclosporine after marrow transplantation." Transplantation 35 (1983): 211-5
Generic Name: amphotericin b
Brand name: Fungizone, Fungizone For Tissue Culture, Amphocin
Synonyms: n.a.
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Gengraf (Capsules, Modified)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Amphocin-Gengraf (Cyclosporine Capsules, Modified)
- Amphocin-Gengraf (Cyclosporine Oral Solution, Modified)
- Amphocin-Gengraf Capsules
- Amphocin-Gengraf Oral
- Amphocin-Gengraf Oral Solution
- Amphocin-Genicin
- Gengraf-Amphojel
- Gengraf-Amphotec
- Gengraf-Amphotericin B
- Gengraf-Amphotericin B (Conventional)
- Gengraf-Amphotericin B (Lipid Complex)
- Gengraf-Amphotericin B Cholesteryl Sulfate Complex