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Amphotericin B (Conventional) and Vfend

Determining the interaction of Amphotericin B (Conventional) and Vfend and the possibility of their joint administration.

Check result:

Amphotericin B (Conventional) <> Vfend

Relevance: 17.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Imidazole and triazole antifungal agents may antagonize the effects of amphotericin. The clinical significance is unknown. Caution is urged if combination therapy is necessary.

References

"Product Information. Abelcet (amphotericin B)." Liposome Company Inc, The, Princeton, NJ.
"Product Information. Ambisome (amphotericin B liposomal)" Nexstar Pharmaceuticals, San Dimas, CA.
Saag MS, Powderly WG, Cloud GA, et al "Comparison of amphotericin B with fluconazole in the treatment of acute AIDS-associated cryptococcal meningitis." N Engl J Med 326 (1992): 83-9
"Product Information. Fungizone (amphotericin B)." Apothecon Inc, Plainsboro, NJ.

Amphotericin B (Conventional)

Generic Name: amphotericin b

Brand name: Fungizone, Fungizone For Tissue Culture, Amphocin

Synonyms: Amphotericin B

What is Amphotericin B (Conventional)?

Vfend

Generic Name: voriconazole

Brand name: Vfend, Vfend

Synonyms: Vfend Injection

What is Vfend?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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