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Amphotericin b lipid complex Intravenous, Injection and Gengraf Capsules

Determining the interaction of Amphotericin b lipid complex Intravenous, Injection and Gengraf Capsules and the possibility of their joint administration.

Check result:

Amphotericin b lipid complex Intravenous, Injection <> Gengraf Capsules

Relevance: 13.08.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using amphotericin B lipid complex together with cycloSPORINE. This can cause serious side effects on your kidneys. Call your doctor if your experience fever, chills, body aches, flu symptoms, and severe pain in your upper stomach spreading to your back. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The potential nephrotoxic effects of cyclosporine and amphotericin B may be additive.

MANAGEMENT: Alternate antifungal therapy is recommended. If these agents must be used concomitantly, renal function should be closely monitored.

References

"Product Information. Abelcet (amphotericin B)." Liposome Company Inc, The, Princeton, NJ.
Cockburn IT, Krupp P "An appraisal of drug interactions with sandimmun." Transplant Proc 21 (1989): 3845-50
"Product Information. Sandimmune (cyclosporine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Kennedy M, Deeg J, Siegel M, et al "Acute renal toxicity with combined use of amphotericin B and cyclosporine after marrow transplantation." Transplantation 35 (1983): 211-5

Amphotericin b lipid complex Intravenous, Injection

Generic Name: amphotericin b lipid complex

Brand name: Abelcet

Synonyms: Amphotericin B (Lipid Complex), Amphotericin B lipid complex

What is Amphotericin b lipid complex Intravenous, Injection?

Gengraf Capsules

Generic Name: cyclosporine

Brand name: Gengraf, Neoral, Sandimmune, Sandimmune

Synonyms: Gengraf (Capsules, Modified), Gengraf

What is Gengraf Capsules?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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