Ampicillin and sulbactam Injection and Minocin
Determining the interaction of Ampicillin and sulbactam Injection and Minocin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using minocycline together with ampicillin. Combining these medications may reduce the effectiveness of ampicillin. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Tetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by penicillins. Antagonism is more likely when low doses of either agent are administered. Therapeutic failure may result.
MANAGEMENT: This combination should be avoided if possible.
- "Product Information. Declomycin (demeclocycline)." Lederle Laboratories, Wayne, NJ.
- "Product Information. Seysara (sarecycline)." Allergan Inc, Irvine, CA.
- Olsson RA, Kirby JC, Romansky MJ "Pneumococcal meningitis in the adult." Ann Intern Med 55 (1961): 545-9
- Jawetz E "Synergism and antagonism among antimicrobial drugs: a personal perspective." West J Med 123 (1975): 87-91
- Lepper MH, Dowling HF "Treatment of pneumococcic meningitis with penicillin compared with penicillin plus aureomycin." Arch Intern Med 88 (1951): 489-94
- Gunnison JB, Coleman VR, Jawetz E "Interference of aureomycin and of terramycin with action of penicillin in vitro." Proc Soc Exp Biol Med 75 (1950): 549-52
Generic Name: ampicillin / sulbactam
Brand name: Unasyn, Unasyn ADD-Vantage
Synonyms: Ampicillin and sulbactam, Ampicillin and Sulbactam
Generic Name: minocycline
Brand name: Dynacin, Minocin, Minocin PAC, Solodyn, Ximino, Minolira, Vectrin, Myrac
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ampicillin and sulbactam Injection-Minocin (Minocycline Capsules and Tablets)
- Ampicillin and sulbactam Injection-Minocin (Minocycline Injection)
- Ampicillin and sulbactam Injection-Minocin (Minocycline Oral Suspension)
- Ampicillin and sulbactam Injection-Minocin Injection
- Ampicillin and sulbactam Injection-Minocin Intravenous
- Ampicillin and sulbactam Injection-Minocin PAC
- Minocin-Ampicillin Capsules
- Minocin-Ampicillin injection
- Minocin-Ampicillin Injection Solution
- Minocin-Ampicillin Oral Suspension
- Minocin-Ampicillin Sodium
- Minocin-Ampicillin Sodium and Sulbactam Sodium