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Ampicillin Capsules and Dalacin C Palmitate Oral

Determining the interaction of Ampicillin Capsules and Dalacin C Palmitate Oral and the possibility of their joint administration.

Check result:
Ampicillin Capsules <> Dalacin C Palmitate Oral
Relevance: 06.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The combination of clindamycin and ampicillin may result in a higher incidence of diarrhea than with either drug alone. The mechanism may be related to additive effects on the gut microflora.

References
  • Brause BD, Romankiewicz JA, Gotz V, Franklin JE Jr, Roberts RB "Comparative study of diarrhea associated with clindamycin and ampicillin therapy." Am J Gastroenterol 73 (1980): 244-8
Ampicillin Capsules

Generic Name: ampicillin

Brand name: Principen, Omnipen-N, Totacillin-N, Ampicillin

Synonyms: Ampicillin

Dalacin C Palmitate Oral

Generic Name: clindamycin

Brand name: Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal, Cleocin

Synonyms: Clindamycin, Clindamycin (Systemic)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle