Ampyra and Indinavir Sulfate

• Generic Name: dalfampridine
• Dosage Forms: tablet, film coated, extended release
• Other Brand Names: Ampyra

Ampyra (dalfampridine) is a potassium channel blocker.

Ampyra is a prescription medicine used to improve walking in adults with multiple sclerosis (MS).

It is not known if Ampyra is safe or effective in children less than 18 years old.

• Generic Name: indinavir
• Dosage Forms: n.a.
• Other Brand Names: Crixivan

Treatment of HIV infection in adults, adolescents, and pediatric patients; used in conjunction with other antiretrovirals.

Experts state indinavir not recommended for initial treatment regimens in antiretroviral-naive adults and adolescents because of inconvenient dosing regimen, fluid requirements, and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir with low-dose ritonavir (ritonavir-boosted indinavir) not recommended for initial therapy in antiretroviral-naive adults and adolescents because of fluid requirements and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir (with or without low-dose ritonavir) not recommended for initial treatment regimens in antiretroviral-naive pediatric patients because of high incidence of hematuria, sterile leukocyturia, and nephrolithiasis in children.