Ampyra and Lamictal XR

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

LamoTRIgine may increase the blood levels and effects of dalfampridine. You may be more likely to experience side effects of dalfampridine such as nausea, insomnia, dizziness, weakness, headache, confusion, and seizures. Contact your doctor if you have increased side effects or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Theoretically, the concomitant use of dalfampridine with drugs that are inhibitors of organic cation transporter 2 (OCT2) may significantly reduce its renal clearance. Dalfampridine is primarily eliminated through renal excretion; approximately 60% of it via active secretion by OCT2 (in vitro). The risk of CNS excitation and seizures may be increased.

MANAGEMENT: Caution is recommended during concomitant use. European product labeling considers concomitant use contraindicated.

Ampyra

Generic Name: dalfampridine

Brand name: Ampyra

Synonyms: n.a.

What is Ampyra?

Lamictal XR

Generic Name: lamotrigine

Brand name: Lamictal, Lamictal ODT, Lamictal XR, Subvenite, Lamictal, Lamictal ODT, Lamictal XR, Lamictal CD, LaMICtal Starter Kit, LaMICtal ODT Patient Titration Kit, LaMICtal XR Patient Titration Kit, LamoTRIgine Starter Kit, Subvenite Starter Kit

Synonyms: n.a.

What is Lamictal XR?