Amrix and Mipomersen

• Generic Name: cyclobenzaprine
• Dosage Forms: capsule, extended release
• Other Brand Names: Amrix, Comfort Pac with Cyclobenzaprine, Fexmid, Flexeril

Amrix is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.

Amrix is used together with rest and physical therapy to relieve muscle spasms caused by painful conditions such as an injury.

Amrix may also be used for purposes not listed in this medication guide.

• Generic Name: mipomersen
• Dosage Forms: n.a.
• Other Brand Names: Kynamro

Mipomersen is a cholesterol-lowering medication. It reduces blood levels of "bad" cholesterol, such as low-density lipoprotein (LDL), apolipoprotein-B (apo-B), or non-high-density lipoprotein (non-HDL).

Mipomersen is used together with a low-fat diet and other treatments to lower total cholesterol in people with homozygous familial hypercholesterolemia (an inherited type of high cholesterol). Mipomersen is not for use in people with heterozygous familial hypercholesterolemia.

It is not known whether mipomersen will lower your risk of heart disease.

Mipomersen is available only from a certified pharmacy under a special program called Kynamro REMS. Your doctor must be registered in the program in order to prescribe mipomersen for you.

Mipomersen may also be used for purposes not listed in this medication guide.