Anagrelide hydrochloride and Bayer Low Strength
Determining the interaction of Anagrelide hydrochloride and Bayer Low Strength and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using aspirin together with anagrelide may increase the risk of bleeding. Call your doctor promptly if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Anagrelide and aspirin may potentiate each other's antiplatelet effects when they are coadministered. In two clinical studies with healthy subjects, the administration of single-dose anagrelide 1 mg and aspirin 900 mg or repeat dose once-daily anagrelide 1 mg with aspirin 75 mg resulted in greater antiplatelet aggregation effects than administration of aspirin alone. There were no effects on bleeding time, prothrombin time (PT), or activated partial thromboplastin time (aPTT) with the single-dose aspirin and anagrelide regimen. Major hemorrhages have been reported in some patients with essential thrombocythemia who received both aspirin and anagrelide.
MANAGEMENT: Before initiation of combination treatment, the risks and benefits should be assessed, especially in patients who have a high risk for hemorrhage and/or whose platelet counts are greater than 1000 x 10(9)/L.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Agrylin (anagrelide)." Roberts Pharmaceutical Corporation, Eatontown, NJ.
- Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
Generic Name: anagrelide
Brand name: Agrylin
Synonyms: Anagrelide
Generic Name: aspirin
Brand name: Bayer Low Strength, Ecotrin, Arthritis Pain, Aspir 81, Aspir-Low, Bayer Childrens Aspirin, Durlaza, Ecpirin, Fasprin, Halfprin, Miniprin, Aspiritab, Bayer, Bayer Children's, St. Joseph 81 mg Adult
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Anagrelide hydrochloride-Bayer Oral
- Anagrelide hydrochloride-Bayer PM
- Anagrelide hydrochloride-Bayer Select Decongestant
- Anagrelide hydrochloride-BayGam
- Anagrelide hydrochloride-Bayhep B
- Anagrelide hydrochloride-Bayrab
- Bayer Low Strength-Anakinra
- Bayer Low Strength-Anakinra Subcutaneous
- Bayer Low Strength-Analgesic Balm Greaseless
- Bayer Low Strength-Analpram Advanced
- Bayer Low Strength-Analpram E
- Bayer Low Strength-Analpram E Cream