Anagrelide hydrochloride and Green tea

• Generic Name: anagrelide
• Dosage Forms: n.a.
• Other Brand Names: Agrylin

Reduction of elevated platelet counts and associated risk of thromboembolic and hemorrhagic events in patients with thrombocythemia secondary to essential thrombocythemia (ET) and other myeloproliferative disorders. Has been designated an orphan drug by FDA for the treatment of ET.

Management of ET generally based on a risk-stratification approach. Treatment with a cytoreductive agent (e.g., anagrelide, hydroxyurea) usually reserved for patients at high risk (i.e., age >60 years, previous history of thrombosis, and/or platelet count ≥1,500,000/mm3) of developing thromboembolic and/or hemorrhagic complications. Some clinicians also recommend cytoreductive therapy in intermediate-risk ET patients (e.g., 40–60 years of age, platelet count >1,000,000/mm3, and cardiovascular risk factor [smoking, arterial hypertension, hypercholesterolemia, or diabetes mellitus] or familial thrombophilia).

Hydroxyurea (often combined with low-dose aspirin) generally considered drug of choice in high-risk patients with ET because of proven efficacy and infrequent acute toxicity. However, because of potential leukemogenic effects with hydroxyurea when used long term or sequentially with other cytotoxic drugs, anagrelide or interferon alfa suggested as alternative therapy in high-risk patients, particularly younger patients (<40–60 years of age), and in those who do not respond to or cannot tolerate hydroxyurea. Consider cautious use of low-dose aspirin concomitantly with anagrelide based on relative risks of thrombosis and arterial hemorrhage in individual patients. (See Specific Drugs or Foods under Interactions.)

• Generic Name: green tea
• Dosage Forms: n.a.
• Other Brand Names:

Green tea is a product made from the Camellia sinesis plant and it is also known as Camellia theifera, Constituant Polyphénolique de Thé Vert, CPTV, EGCG, Epigallo Catechin Gallate, Extrait de Camellia Sinensis, Extrait de Thé Vert, Extrait de Thea Sinensis, Green Sencha, Green Tea Extract, Green Tea Polyphenolic Fraction, GTP, GTPF, Japanese Tea, Kunecatechins, Poly E, Polyphenon E, PTV, Té Verde, Tea, Tea Extract, Tea Green, Thé de Camillia, Thé Japonais, Thé Vert, Thé Vert Sensha, Thea bohea, Thea sinensis, Thea viridis, Yame Green Tea, Yame Tea, and other names.

Green tea has been used in alternative medicine as a likely effective aid in treating genital warts, high cholesterol, and maintaining mental alertness.

Green tea has been used in alternative medicine as a possibly effective aid in treating clogged arteries, endometrial and ovarian cancer, low blood pressure, osteoporosis, changes in cervical cells due to human papiloma virus (HPV), white patches in the gums and the prevention of Parkinson's disease.

Other uses not proven with research have included various cancers (bladder, esophagus, pancreas, breast, colon, stomach, leukemia, mouth, prostate, lung); acne, heart disease, diabetes, infertility, high blood presure, obesity, respiratory infections, improvement of athletic perfomrance, wrinkles and others.

It is not certain whether green tea is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Green tea should not be used in place of medication prescribed for you by your doctor.

Green tea is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Green tea may also be used for purposes not listed in this product guide.