Anakinra Subcutaneous and Tegsedi

• Generic Name: anakinra
• Dosage Forms: n.a.
• Other Brand Names: Kineret

Anakinra injection is used alone or together with other medicines to treat signs and symptoms of moderately to severely active rheumatoid arthritis in adult patients who have not been helped by other medicines (e.g., DMARDs). Anakinra is also used to treat a rare genetic disorder called neonatal-onset multisystem inflammatory disease (NOMID). NOMID is the most severe form of a condition called cryopyrin-associated periodic syndrome (CAPS).

Anakinra is available only with your doctor's prescription.

• Generic Name: inotersen
• Dosage Forms: injection, solution
• Other Brand Names: Tegsedi

Tegsedi (inotersen) works by decreasing a protein called transthyretin (TTR, made primarily in the liver). Hereditary transthyretin-mediated amyloidosis (hATTR) is a rare condition in which abnormal deposits of TTR protein build up in many parts of the body, interfering with normal function.

Tegsedi injection is used to treat polyneuropathy (damage of multiple nerves throughout the body) in adults with hATTR. This medicine can help reduce symptoms such as pain, numbness, tingling, abnormal heartbeats, diarrhea, constipation, weakness, and problems with movement in your arms or legs.

Tegsedi is available only from a certified pharmacy under a special program.