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Anectine and Carbamazepine Extended-Release Capsules (Carbatrol)

Determining the interaction of Anectine and Carbamazepine Extended-Release Capsules (Carbatrol) and the possibility of their joint administration.

Check result:
Anectine <> Carbamazepine Extended-Release Capsules (Carbatrol)
Relevance: 14.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using succinylcholine together with carBAMazepine may increase the effects of succinylcholine. Contact your doctor if you experience increased side effects or if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Chronic administration of anticonvulsants, including phenytoin and/or carbamazepine may prolong the effects of succinylcholine. The mechanism may be related to anticonvulsant-induced up-regulation of acetylcholine receptors.

MANAGEMENT: Close observation for reduced or prolonged succinylcholine effect is recommended if this drug must be used in a patient receiving chronic anticonvulsant therapy.

References
  • Melton AT, Antognini JF, Gronert GA "Prolonged duration of succinylcholine in patients receiving anticonvulsants: evidence for mild up-regulation of acetylcholine receptors?" Can J Anaesth 40 (1993): 939-42
Anectine

Generic Name: succinylcholine

Brand name: Anectine, Quelicin

Synonyms: n.a.

Carbamazepine Extended-Release Capsules (Carbatrol)

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: Carbamazepine, CarBAMazepine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.