Annovera vaginal ring and DAUNOrubicin and Cytarabine

• Generic Name: ethinyl estradiol / segesterone
• Dosage Forms: vaginal ring
• Other Brand Names: Annovera

Annovera vaginal system (ring) is used as contraception to prevent pregnancy. One vaginal ring may be reused for up to 1 year.

Annovera may also be used for purposes not listed in this medication guide.

• Generic Name: cytarabine liposomal / daunorubicin liposomal
• Dosage Forms: n.a.
• Other Brand Names: Vyxeos

Treatment of newly diagnosed therapy-related AML (t-AML; secondary AML) or AML with myelodysplasia-related changes (AML-MRC) in adults (designated an orphan drug by FDA for this use).

May be used for remission induction as well as consolidation therapy.

Evidence supporting efficacy is based principally on a study performed in patients with high-risk AML (i.e., patients >60 years of age with t-AML or AML-MRC).