Annovera vaginal ring and Lorazepam Oral Concentrate
Determining the interaction of Annovera vaginal ring and Lorazepam Oral Concentrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Oral contraceptives may increase the clearance rate of benzodiazepines that undergo glucuronidation (such as lorazepam, oxazepam, and temazepam). Close observation for signs and symptoms of altered benzodiazepine effect is recommended.
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- Billedeau SM, Holder CL, Getek TA "High-performance liquid chromatography of the antihistamine pyrilamine and its N-oxide using electrochemical detection." J Chromatogr 534 (1990): 151-9
- Patwardhan RV, Mitchell MC, Johnson RF, Schenker S "Differential effects of oral contraceptive steroids on the metabolism of benzodiazepines." Hepatology 3 (1983): 248-53
- Abernethy DR, Greenblatt DJ, Divoll M, Arendt R, Ochs HR, Shader RI "Impairment of diazepam metabolism by low-dose estrogen-containing oral-contraceptive steroids." N Engl J Med 306 (1982): 791-2
- Stoehr GP, Kroboth PD, Juhl RP, Wender DB, Phillips JP, Smith RB "Effect of oral contraceptives on triazolam, temazepam, alprazolam, and lorazepam kinetics." Clin Pharmacol Ther 36 (1984): 683-90
Generic Name: ethinyl estradiol / segesterone
Brand name: Annovera
Synonyms: Annovera (vaginal ring), Annovera
Generic Name: lorazepam
Brand name: Ativan, Lorazepam Intensol
Synonyms: Lorazepam, LORazepam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Annovera vaginal ring-Lorazepam Oral Solution
- Annovera vaginal ring-Lorazepam Tablets
- Annovera vaginal ring-Lorbrena
- Annovera vaginal ring-Lorcaserin
- Annovera vaginal ring-Lorcaserin Extended-Release Tablets
- Annovera vaginal ring-Lorcaserin Hydrochloride
- Lorazepam Oral Concentrate-Anodyne LPT
- Lorazepam Oral Concentrate-AnodyneRx
- Lorazepam Oral Concentrate-Anolor 300 Oral
- Lorazepam Oral Concentrate-Anoro Ellipta
- Lorazepam Oral Concentrate-Ansaid
- Lorazepam Oral Concentrate-Antabuse