Antabuse and Zyvox (Linezolid Suspension)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using disulfiram together with medications like linezolid has rarely resulted in delirium and other psychiatric reactions. Contact your doctor if your condition changes or you experience increased or unusual side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Delirium has been observed during the coadministration of disulfiram and monoamine oxidase inhibitors (MAOIs). The mechanism of interaction has not been determined. Clinical evidence is limited to one case report in which tranylcypromine was added to a regimen including disulfiram and lithium.

MANAGEMENT: Until further data are available, it may be appropriate to monitor patients for evidence of delirium or other unusual psychiatric reactions when disulfiram is given with MAOIs or other agents that possess MAOI activity (e.g., furazolidone, linezolid, methylene blue, procarbazine). If symptoms occur, the MAOI should not be discontinued abruptly because of the risk of withdrawal symptoms.

Antabuse

Generic Name: disulfiram

Brand name: Antabuse

Synonyms: n.a.

What is Antabuse?

Zyvox (Linezolid Suspension)

Generic Name: linezolid

Brand name: Zyvox

Synonyms: Zyvox

What is Zyvox (Linezolid Suspension)?