Antithrombin alfa and Hydrocodone and Chlorpheniramine Solution

• Generic Name: antithrombin (recombinant)
• Dosage Forms: n.a.
• Other Brand Names: ATryn

Prevention of perioperative and peripartum thromboembolism in patients with congenital antithrombin III deficiency; designated an orphan drug by FDA for use in these conditions.

Short-term thromboprophylaxis with an appropriate anticoagulant recommended in patients with congenital antithrombin III deficiency during high-risk situations (e.g., surgery, pregnancy, postpartum period); antithrombin III concentrates may be used when anticoagulant therapy is neither feasible (e.g., due to a bleeding risk) nor sufficient.

Not indicated for treatment of thromboembolic events.

Has been used for management of heparin resistance during cardiopulmonary bypass (CPB).

May reduce requirements for fresh frozen plasma and additional heparin during CPB.

• Generic Name: chlorpheniramine / hydrocodone
• Dosage Forms: oral solution
• Other Brand Names: TussiCaps, Tussionex PennKinetic, S-T Forte 2, HyTan, Novasus, Vituz

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Hydrocodone is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Chlorpheniramine and hydrocodone is a combination medicine used to treat runny nose, sneezing, itching, watery eyes, and cough caused by allergies, the common cold, or the flu.

Chlorpheniramine and hydrocodone may also be used for purposes not listed in this medication guide.