Antithrombin alfa and Nivestym

• Generic Name: antithrombin (recombinant)
• Dosage Forms: n.a.
• Other Brand Names: ATryn

Prevention of perioperative and peripartum thromboembolism in patients with congenital antithrombin III deficiency; designated an orphan drug by FDA for use in these conditions.

Short-term thromboprophylaxis with an appropriate anticoagulant recommended in patients with congenital antithrombin III deficiency during high-risk situations (e.g., surgery, pregnancy, postpartum period); antithrombin III concentrates may be used when anticoagulant therapy is neither feasible (e.g., due to a bleeding risk) nor sufficient.

Not indicated for treatment of thromboembolic events.

Has been used for management of heparin resistance during cardiopulmonary bypass (CPB).

May reduce requirements for fresh frozen plasma and additional heparin during CPB.

• Generic Name: filgrastim
• Dosage Forms: injection, solution
• Other Brand Names: Neupogen, Neupogen SingleJect, Nivestym, Zarxio

Nivestym is a man-made form of a protein that stimulates the growth of white blood cells in your body. White blood cells help your body fight against infection.

Nivestym is used to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, or by other conditions.

Nivestym may also be used for purposes not listed in this medication guide.