Antithrombin alfa and Secobarbital

• Generic Name: antithrombin (recombinant)
• Dosage Forms: n.a.
• Other Brand Names: ATryn

Prevention of perioperative and peripartum thromboembolism in patients with congenital antithrombin III deficiency; designated an orphan drug by FDA for use in these conditions.

Short-term thromboprophylaxis with an appropriate anticoagulant recommended in patients with congenital antithrombin III deficiency during high-risk situations (e.g., surgery, pregnancy, postpartum period); antithrombin III concentrates may be used when anticoagulant therapy is neither feasible (e.g., due to a bleeding risk) nor sufficient.

Not indicated for treatment of thromboembolic events.

Has been used for management of heparin resistance during cardiopulmonary bypass (CPB).

May reduce requirements for fresh frozen plasma and additional heparin during CPB.

• Generic Name: secobarbital
• Dosage Forms: n.a.
• Other Brand Names: Seconal Sodium, Seconal

Secobarbital is a barbiturate (bar-BIT-chur-ate) that slows the activity of your brain and nervous system.

Secobarbital is used short-term to treat insomnia, or as a sedative before surgery.

Secobarbital may also be used for purposes not listed in this medication guide.