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Antivenin (Latrodectus mactans) (Equine) and InnoPran XL

Determining the interaction of Antivenin (Latrodectus mactans) (Equine) and InnoPran XL and the possibility of their joint administration.

Check result:
Antivenin (Latrodectus mactans) (Equine) <> InnoPran XL
Relevance: 27.03.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using propranolol together with antivenin (black widow spider) may increase the severity and duration of anaphylactic reactions during the administration of antivenin (black widow spider). Contact your doctor if you experience increased side effects or if you have any breathing difficulties. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Beta-adrenergic blockers (including ophthalmic formulations) may increase the severity and duration of acute anaphylactic reactions to antivenins. In addition, anaphylaxis may be resistant to the usual treatment modalities. The mechanism is unknown.

MANAGEMENT: Patients should be closely monitored for signs of severe, acute hypersensitivity reactions during administration of antivenins, and facilities and equipment for resuscitation, cardiovascular support, and airway management should be immediately available. Clinicians should be aware that larger doses of epinephrine or other adrenergic agents may be required.

References
  • "Product Information. Antivenin (Latrodectus Mactans) (black widow spider species antivenin)." Merck & Company Inc, West Point, PA.
  • "Product Information. Crofab (antivenin (crotalidae) polyvalent)" Savage Laboratories, Melville, NY.
Antivenin (Latrodectus mactans) (Equine)

Generic Name: antivenin (black widow spider)

Brand name:

Synonyms: Antivenin

InnoPran XL

Generic Name: propranolol

Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.