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Anturane and Nicotinex

Determining the interaction of Anturane and Nicotinex and the possibility of their joint administration.

Check result:
Anturane <> Nicotinex
Relevance: 24.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Niacin may reduce the uricosuric effect of sulfinpyrazone. The mechanism is not entirely clear, but probably involves reduction of the inhibitory effect of sulfinpyrazone on renal tubular reabsorption of uric acid. Since hyperuricemia is a potential side effect of niacin, an alternative antihyperlipidemia agent should be used.

References
  • Gershon SL, Fox IH "Pharmacologic effects of nicotinic acid on human purine metabolism." J Lab Clin Med 84 (1974): 179-86
Anturane

Generic Name: sulfinpyrazone

Brand name:

Synonyms: n.a.

Nicotinex

Generic Name: niacin

Brand name: B-3-50, B3-500-Gr, Niacin SR, Niacor, Niaspan ER, Slo-Niacin

Synonyms: Nicotinex (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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