Apo-Cyclosporine Oral and Etelcalcetide Hydrochloride

• Generic Name: cyclosporine
• Dosage Forms: n.a.
• Other Brand Names: Gengraf, Neoral, Sandimmune, Sandimmune

Cyclosporine is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). It belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Cyclosporine works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.

Cyclosporine is also used to treat severe rheumatoid arthritis in patients who have failed treatment with methotrexate. This medicine is also used to treat adults with severe plaque psoriasis after other treatments (eg, PUVA, retinoids, methotrexate) failed.

Cyclosporine is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

• Generic Name: etelcalcetide
• Dosage Forms: n.a.
• Other Brand Names: Parsabiv

Treatment of secondary hyperparathyroidism associated with chronic renal disease in patients undergoing hemodialysis.

Additional studies needed to determine effects on clinical outcomes, including cardiovascular morbidity and mortality.

Safety and efficacy not established in patients with chronic renal disease who are not undergoing hemodialysis; use not recommended in these patients.

Safety and efficacy not established in patients with parathyroid carcinoma or primary hyperparathyroidism; use not recommended in these patients.