Apo-Sulfatrim and Digoxin Injection
Determining the interaction of Apo-Sulfatrim and Digoxin Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Trimethoprim may decrease the renal tubular secretion of digoxin. Serum digoxin levels may be increased. The patient should be monitored for digoxin toxicity, and digoxin dosage should be reduced as necessary. Serum digoxin levels usually do not need to be checked unless toxicity is suspected. Patients should be advised to notify their physician if they experience nausea, anorexia, visual changes, slow pulse, or irregular heartbeats.
- Petersen P, Kastrup J, Bartram R, Hansen J "Digoxin-trimethoprim interaction." Acta Med Scand 217 (1985): 423-7
Generic Name: sulfamethoxazole / trimethoprim
Brand name: Bactrim, Bactrim DS, Bactrim IV, Septra IV, SMZ-TMP DS, Sulfatrim Pediatric, Septra, Sulfatrim, Bethaprim, Cotrim, Uroplus, Uroplus DS, Cotrim DS, Bactrim Pediatric, Bethaprim Pediatric, Sulfatrim Suspension, Cotrim Pediatric, Septra DS
Synonyms: Sulfamethoxazole and trimethoprim, Sulfamethoxazole and Trimethoprim
Generic Name: digoxin
Brand name: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin
Synonyms: Digoxin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Apo-Sulfatrim-Digoxin Intravenous
- Apo-Sulfatrim-Digoxin Oral Solution
- Apo-Sulfatrim-Digoxin oral/injection
- Apo-Sulfatrim-Digoxin Tablets
- Apo-Sulfatrim-Dihydro CP Syrup
- Apo-Sulfatrim-Dihydrocodeine BPM Phenyleph HCl
- Digoxin Injection-Apokyn
- Digoxin Injection-Apomorphine
- Digoxin Injection-Apomorphine Ampules
- Digoxin Injection-Apomorphine Cartridges and Pens
- Digoxin Injection-Apomorphine Hydrochloride
- Digoxin Injection-Apomorphine Subcutaneous