Apomorphine Hydrochloride and Avelumab

• Generic Name: apomorphine
• Dosage Forms: n.a.
• Other Brand Names: Apokyn, APO-Go, APO-Go Pen, Uprima

Acute, intermittent treatment of episodes of hypomobility (i.e., “off” episodes, including end-of-dose “wearing off” and unpredictable “on-off” episodes) associated with advanced Parkinson’s disease (designated an orphan drug by FDA for this use).

Used as an adjunct to other antiparkinsonian agents (e.g., levodopa, oral dopamine receptor agonists).

Formerly used to induce vomiting in the early management of acute oral drug overdose and in certain cases of oral poisoning (dose: 5–6 mg sub-Q).

• Generic Name: avelumab
• Dosage Forms: n.a.
• Other Brand Names: Bavencio

Avelumab is used to treat a type of skin cancer called Merkel cell carcinoma in adults and children at least 12 years old, when the cancer has spread to other parts of the body (metastatic).

Avelumab is also used to treat a certain type of cancer of the bladder or urinary tract that has spread or cannot be removed with surgery. Avelumab is given for this condition after platinum cancer medicines did not work or have stopped working.

Avelumab is also used alone or in combination with another medicine called axitinib to treat advanced kidney cancer that has spread or cannot be removed with surgery.

Avelumab may also be used for purposes not listed in this medication guide.