Apomorphine Hydrochloride and Invokana

• Generic Name: apomorphine
• Dosage Forms: n.a.
• Other Brand Names: Apokyn, APO-Go, APO-Go Pen, Uprima

Acute, intermittent treatment of episodes of hypomobility (i.e., “off” episodes, including end-of-dose “wearing off” and unpredictable “on-off” episodes) associated with advanced Parkinson’s disease (designated an orphan drug by FDA for this use).

Used as an adjunct to other antiparkinsonian agents (e.g., levodopa, oral dopamine receptor agonists).

Formerly used to induce vomiting in the early management of acute oral drug overdose and in certain cases of oral poisoning (dose: 5–6 mg sub-Q).

• Generic Name: canagliflozin
• Dosage Forms: tablet, film coated
• Other Brand Names: Invokana

Invokana (canagliflozin) is an oral diabetes medicine that helps control blood sugar levels. Canagliflozin works by helping the kidneys get rid of glucose from your bloodstream.

Invokana is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Invokana is used to reduce the risk of cardiovascular events (including heart attack, stroke or death) in adults with type 2 diabetes and established cardiovascular disease.

Invokana is also used to reduce the risk of end stage kidney disease (ESKD), worsening of kidney function, cardiovascular death, and hospitalization for heart failure in adults with type 2 diabetes and diabetic kidney disease.

Invokana is not for treating type 1 diabetes.