Apraclonidine and Glasdegib Maleate

• Generic Name: apraclonidine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Iopidine

• It is used to lower high eye pressure.

• Generic Name: glasdegib
• Dosage Forms: n.a.
• Other Brand Names: Daurismo

Glasdegib maleate is a hedgehog pathway inhibitor indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of intensive induction chemotherapy.

Glasdegib maleate has not been studied in patients with the comorbidities of severe renal impairment or moderate-to-severe hepatic impairment.