Apraclonidine Hydrochloride and Bevespi Aerosphere

• Generic Name: apraclonidine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Iopidine

Apraclonidine 1% is used prophylactically to prevent or reduce intraoperative and postoperative increases in intraocular pressure (IOP) before and after ocular laser surgery (e.g., argon laser trabeculoplasty, argon laser iridotomy, neodymium yttrium aluminum garnet [Nd:YAG] laser posterior capsulotomy).

Apraclonidine 0.5% is used for short-term (<1 month) adjunctive therapy in patients with open-angle glaucoma receiving maximally tolerated drug therapy (i.e., a topical β-adrenergic blocking agent in conjunction with a systemically administered carbonic anhydrase inhibitor and a sympathomimetic and/or a parasympathomimetic agent) who require additional reduction in IOP.

• Generic Name: formoterol / glycopyrrolate
• Dosage Forms: aerosol, metered
• Other Brand Names: Bevespi Aerosphere

Bevespi Aerosphere is an inhalation aerosol containing a combination of formoterol and glycopyrrolate. Formoterol is a bronchodilator. Glycopyrrolate is an anticholinergic. These medications work by relaxing muscles in the airways to improve breathing.

Bevespi Aerosphere is used to prevent airflow obstruction or bronchospasm and reduce flare-ups in adults with COPD (chronic obstructive pulmonary disease), including bronchitis and emphysema.

Bevespi Aerosphere is not for use in treating asthma.

Formoterol may increase the risk of death in people with asthma, but the risk in people with COPD is not known. Talk with your doctor about your individual risk.