Apraclonidine Hydrochloride and Nithiodote

• Generic Name: apraclonidine ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Iopidine

Apraclonidine 1% is used prophylactically to prevent or reduce intraoperative and postoperative increases in intraocular pressure (IOP) before and after ocular laser surgery (e.g., argon laser trabeculoplasty, argon laser iridotomy, neodymium yttrium aluminum garnet [Nd:YAG] laser posterior capsulotomy).

Apraclonidine 0.5% is used for short-term (<1 month) adjunctive therapy in patients with open-angle glaucoma receiving maximally tolerated drug therapy (i.e., a topical β-adrenergic blocking agent in conjunction with a systemically administered carbonic anhydrase inhibitor and a sympathomimetic and/or a parasympathomimetic agent) who require additional reduction in IOP.

• Generic Name: sodium nitrite / sodium thiosulfate
• Dosage Forms: injection
• Other Brand Names: Nithiodote

Nithiodote is a combination medicine that is used as an antidote to cyanide poisoning. This medicine works by helping cells in the body convert cyanide to a form that can be removed from the body through urination.

Nithiodote is used in an emergency to treat cyanide poisoning. This type of poisoning can occur if you are exposed to smoke from a house or industrial fire, if you swallow or breathe in cyanide, or if you get cyanide on your skin.

Nithiodote may also be used for purposes not listed in this medication guide.