Apriso and Glasdegib Maleate

• Generic Name: mesalamine
• Dosage Forms: capsule, extended release
• Other Brand Names: Apriso, Asacol HD, Delzicol, Lialda, Pentasa, Canasa, Canasa Pac, Rowasa, SfRowasa

Apriso (mesalamine) affects a substance in the body that causes inflammation, tissue damage, and diarrhea.

Apriso is used to treat mild to moderate ulcerative colitis in patients 18 years of age and older.

Apriso is also used to prevent the symptoms of ulcerative colitis from recurring.

• Generic Name: glasdegib
• Dosage Forms: n.a.
• Other Brand Names: Daurismo

Glasdegib maleate is a hedgehog pathway inhibitor indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of intensive induction chemotherapy.

Glasdegib maleate has not been studied in patients with the comorbidities of severe renal impairment or moderate-to-severe hepatic impairment.