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Aptiom and Lamictal CD

Determining the interaction of Aptiom and Lamictal CD and the possibility of their joint administration.

Check result:

Aptiom <> Lamictal CD

Relevance: 25.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with eslicarbazepine acetate has been shown to modestly decrease the plasma concentrations of lamotrigine. The mechanism of interaction has not been established. In healthy study subjects, lamotrigine systemic exposure (AUC) decreased by an average of 15% when coadministered with eslicarbazepine acetate 1200 mg once daily. This change is not considered clinically significant, and no dosage adjustments are required.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Aptiom (eslicarbazepine)." Sunovion Pharmaceuticals Inc, Marlborough, MA.

Aptiom

Generic Name: eslicarbazepine

Brand name: Aptiom

Synonyms: n.a.

What is Aptiom?

Lamictal CD

Generic Name: lamotrigine

Brand name: Lamictal, Lamictal ODT, Lamictal XR, Lamictal, Lamictal ODT, Lamictal XR, Subvenite, Lamictal CD, LaMICtal Starter Kit, LaMICtal ODT Patient Titration Kit, LaMICtal XR Patient Titration Kit, LamoTRIgine Starter Kit, Subvenite Starter Kit

Synonyms: Lamictal CD (Oral)

What is Lamictal CD?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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