Aptivus (Tipranavir Capsules) and Microgestin Fe 1/20

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using ethinyl estradiol together with tipranavir may increase your risk of developing a skin rash. If a rash occurs, it is usually mild to moderate. Nevertheless, you should be instructed to contact their doctor promptly. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Use of tipranavir in combination with estrogens may be associated with an increased risk of skin rash. The mechanism has not been described. Mild to moderate rashes including urticarial rash, maculopapular rash, and possible photosensitivity have been reported in 14% of females and 8% to 10% of males receiving tipranavir in combination with low-dose ritonavir in phase 2 and 3 trials. However, in one drug interaction trial, 33% of healthy female volunteers administered a single dose of ethinyl estradiol followed by tipranavir/ritonavir developed a rash. Rash accompanied by joint pain or stiffness, throat tightness, or generalized pruritus has also been reported in both men and women.

MANAGEMENT: Women who use estrogens should be advised of a potentially increased risk of skin rash during concomitant treatment with tipranavir. If a rash occurs, it is usually mild to moderate. Nevertheless, patients should be instructed to contact their physician promptly, as a temporary discontinuation of tipranavir or the estrogen may be necessary.

Aptivus (Tipranavir Capsules)

Generic Name: tipranavir

Brand name: Aptivus

Synonyms: Aptivus

What is Aptivus (Tipranavir Capsules)?

Microgestin Fe 1/20

Generic Name: ethinyl estradiol / norethindrone

Brand name: Blisovi 24 Fe, Blisovi Fe 15/30, Blisovi Fe 1/20, Estrostep Fe, Gildess 24 Fe, Gildess Fe 15/30, Gildess Fe 1/20, Junel Fe 15/30, Junel Fe 1/20, Junel Fe 24, Larin 24 Fe, Larin Fe 15/30, Larin Fe 1/20, Lo Loestrin Fe, Loestrin 24 Fe, Loestrin Fe 15/30, Loestrin Fe 1/20, Lomedia 24 Fe, Microgestin 24 Fe, Microgestin Fe 15/30, Microgestin Fe 1/20, Tarina Fe 1/20, Taytulla, Tilia Fe, Tri-Legest Fe, Blisovi 24 Fe, Femcon Fe, Kaitlib FE, Lo Minastrin Fe, Microgestin 24 Fe, Norinyl 1+35, Ortho-Novum 7/7/7, Tri-Norinyl, Zenchent, femhrt 05 mg/25 mcg, Fyavolv, Jevantique Lo, Jinteli, Femcon Fe, Generess FE, Loestrin 1/20, Ovcon 35, Brevicon

Synonyms: n.a.

What is Microgestin Fe 1/20?